The store that changed Tribeca most is probably the nicest Whole Foods in Manhattan, even when the lunchtime crowds file in. (You can enter on Greenwich, Warren, or West, and depending on what you need, you may want to choose your entrance accordingly.) The groceries are standard Whole Foods fare—tilted toward the healthy, if not necessarily the local—and there’s a lot of non-food stuff, such as vitamins, health and beauty products (more Tom’s of Maine than Crest), clothing, and tote bags. For classic breakfast cereals and mainstream paper products, you’ll want to go to the Food Emporium. The center of the store is devoted to prepared food—complete with a sushi bar—and there’s seating upstairs.